Penegra 100 mg (which contains sildenafil, the same active ingredient as Viagra) is most effective when taken according to the recommended guidelines. Here's the best way to use it:

Take it on an empty stomach: Penegra 100mg works best when taken on an empty stomach, as a heavy meal can delay its onset of action. Ideally, take it about 30 minutes to 1 hour before sexual activity.

Avoid high-fat meals: High-fat meals can slow down the absorption of the medication, reducing its effectiveness. It’s best to avoid heavy, greasy meals right before taking the pill.

Do not take more than one dose per day: Taking more than the recommended dose of 100 mg in a 24-hour period can increase the risk of side effects, such as headaches, dizziness, and changes in vision.

Stay hydrated: Drink plenty of water when taking the medication, as dehydration can sometimes increase side effects like headaches.

Avoid alcohol in excess: While moderate alcohol consumption might not cause significant issues, drinking excessive amounts can impair the effectiveness of the medication and increase the risk of side effects.

In general, following these guidelines and consulting with your doctor about the best way to take Penegra 100 mg for your specific needs is the most effective approach.